David A. Baker, Ph.D.
Dr. Baker cofounded Promentis Pharmaceuticals in 2007 and currently serves as a Director and chairs the Scientific Advisory Board. Dr. Baker is also Associate Professor and Associate Chair in the Department of Biomedical Sciences at Marquette University. He previously served as a postdoctoral fellow at the Medical University of South Carolina in the laboratory of Peter Kalivas. He obtained his Ph.D. at Arizona State University in 1999 and his B.S. at Montana State University in 1992 working in the laboratories of Dr. Janet Neisewander and Dr. Michael Babcock, respectively. Dr. Baker has had an active research career examining the neurobiological basis of diseases of the brain, as evidenced by his 30 publications in the past 18 years and 10 grants or awards over the past six years totaling $2.8M. Dr. Baker was featured in the Marquette Magazine cover story (Winter 2009 issue) “Searching for a Cure for the Brain’s Darkest Diseases” and was a recent recipient of The Business Journal’s Forty under 40 Award, honoring Milwaukee’s up-and-coming leaders. Dr. Baker is the recipient of the 2010 Daniel X. Freedman Award from NARSAD for outstanding basic research achievement.
Peter W. Kalivas, Ph.D.
Dr. Kalivas is Professor and Chair of the Department of Neurosciences at the Medical University of South Carolina in Charleston (1998-present). He is best known for his work to elucidate the brain molecules and neurocircuitry that underlie addiction, with a focus on characterizing the neuroplasticity produced by chronic use of addictive drugs in the prefrontal cortex and its glutamatergic projections to the basal ganglia. Dr. Kalivas’ work is highlighted in over 400 publications and Dr. Kalivas has served as editor of six books that focus on the cellular mechanisms and brain circuitry mediating psychiatric disorders. He has received a great number of national and international awards and is a Distinguished University Professor at both the Medical University of South Carolina and Washington State University. He is a member of the Scientific Advisory Board for the National Alliance for Research in Schizophrenia and Depression, and chairs the Scientific Advisory Board for the Medications Development Program in the National Institute on Drug Abuse. He also serves as editor or is on the editorial board of six major journals in the field of neuroscience. He received his Ph.D. in Pharmacology from the University of Washington in Seattle in 1980.
Daniel C. Javitt, M.D., Ph.D.
Dr. Javitt is a Professor in the Department of Psychiatry and Neuroscience at the Columbia University College of Physicians and Surgeons. He was an early proponent of the NMDA model of schizophrenia and is a leader in NMDA-based treatment development. He has published over 200 original research articles on topics related to schizophrenia, with over 4400 cumulative citations. He has received numerous honors for his work, including research awards from the American Psychiatric Association, the American College of Neuropsychopharmacology, the Society for Biological Psychiatry, and the Child Welfare League of America. His work has been supported by the National Institute of Health, NARSAD and the Stanley Foundation.
Herbert Y. Meltzer, M.D.
Dr. Meltzer is Professor in Psychiatry and Behavioral Sciences and Physiology at Northwestern University Keinberg School of Medicine in Chicago. He is also chair of the Young Investigator Grant Review Committee for NARSAD. He is chairman of the International Psychopharmacology Algorithm Project (www.IPAP.org). Dr. Meltzer received his BA from Cornell University, an MA in Chemistry from Harvard, and his MD from Yale University. Dr. Meltzer has been President of the American College of Neuropsychopharmacology (ACNP) and the Collegium International Neuro-psychopharmacologicum (CINP). He served as editor of Psychopharmacology: The Third Generation of Progress and co-editor of the ACNP journal, Neuropsychopharmacology, and is a member of the editorial board of numerous scientific journals. Dr. Meltzer is the recipient of a great number of awards and prizes. His research interests include: clinical and basic psychopharmacology, with an emphasis on antipsychotic drug efficacy, safety and tolerability, the mechanism of action of antipsychotic drugs, genetic factors in schizophrenia and pharmacogenomics, prevention of suicide in schizophrenia, and cognitive impairment in schizophrenia.
Chad E. Beyer, Ph.D., MBA
Dr. Beyer has been the President & CEO of Promentis since early 2013. He is a pharmaceutical professional with more than 15 years experience in the research, discovery and business development of medications aimed to treat CNS and neurological disorders. For more than a decade, Dr. Beyer worked in the Discovery Neuroscience group at Wyeth Pharmaceuticals in Princeton, NJ, holding positions of increasing responsibility including serving as the Head of Neurochemistry and leading the Psychiatry Task Force. During his career at Wyeth, Dr. Beyer led several early-stage drug discovery teams, managed a group responsible for contributing to the submission of more than 30 INDs and provided supporting data for the commercialization and life-cycle management of two blockbuster medications: Effexor® and Pristiq®. Dr. Beyer holds a Ph.D. in Neuropharmacology from LSU Medical Center and an MBA from the Rutgers Business School. Notably, Dr. Beyer has authored more than 70 manuscripts, 3 patents, co-edited "Next Generation Antidepressants" and is co-founder of the journal "Technology Transfer & Entrepreneurship." Dr. Beyer is also an adjunct faculty member at Thomas Jefferson University in Philadelphia where he teaches "Bioventure Management" and the business of doing science.
Michael P. Neary, B.S.
Michael Neary is currently Director of Research & Development at Promentis. Since beginning work at Promentis in 2010, Mr. Neary has taken on an increasingly important role within the company; he now oversees the Promentis day-to-day research efforts, coordinates the activities of Promentis' collaborators, and continues to work toward advancing Promentis' scientific platform and lead molecules closer to the patients who suffer from these devastating disorders. Prior to joining Promentis, Mr. Neary worked at Roche Madison on programs focused on the development of RNAi delivery platforms. Mr. Neary holds a Biochemistry degree from the University of Wisconsin (Madison).
Sheldon Garrison, Ph.D.
Dr. Garrison joined Promentis in 2014 and serves as Director, Pediatric and Rare Diseases. He has 11 years of neuroscience research experience that has focused on neuromuscular development, sensory biology and pain. Dr. Garrison earned a Ph.D. in Biological Sciences from the University of Wisconsin – Milwaukee and a B.S. from the University of Wisconsin – Madison. He has received multiple competitive financial awards and has authored eight publications over the past four years. Dr. Garrison has previously worked as a Postdoctoral fellow at the Medical College of Wisconsin and has held biotech consulting positions with the Postdoc Industry Consultants (PICO), DNASTAR, Inc and Sequencing Singapore. Dr. Garrison has also served as an instructor at the University of Wisconsin – Milwaukee and Milwaukee Area Technical College.
Matthew B. Tabakin, B.A.
Mr. Tabakin currently works as a Research & Development Assistant at Promentis. Since joining the Promentis Team in August 2013, Mr. Tabakin has primarily focused on analytical (HPLC) research, the in vitro evaluation of proprietary molecules and various competitive landscape projects. Further, Mr. Tabakin's main functions are to contribute to the advancement of Promentis’ R&D platform while adding value to Promentis' growing scientific database and projects related to a variety of CNS disorders. Mr. Tabakin holds an Economics degree from Emory University and he is thrilled to begin his professional career at Promentis Pharmaceuticals.
XiaoQian Liu, Ph.D.
Dr. Liu is a Postdoctoral Research Fellow at Promentis via a unique collaboration between Promentis and the Postdoc Industry Consultant (PICO) group, a biotechnology initiative of the Medical College of Wisconsin. The aim of Dr. Liu's work is to identify new potential areas of research for Promentis with an eye towards applying Promentis' proprietary compounds to the rare and orphan disease space. Dr. Liu got her Ph.D. in neuroscience from Marquette University, and she also works as a Postdoctoral fellow at the Medical College of Wisconsin where her research has been focusing on cellular and molecular neuroscience in neurodegenerative and psychiatric disorder models.
Brian Hoffman, Ph.D.
Dr. Brian Hoffmann is a Postdoctoral Research Fellow at Promentis via the Medical College of Wisconsin PICO group. The aim of Dr. Hoffmann’s work is to explore alternative mechanisms of implementation for the ongoing science at Promentis with a specific focus on rare and orphan indications. In parallel, Dr. Hoffmann focuses on the off-target effects of pharmaceuticals and impaired cardiovascular function through his Postdoctoral Fellowship at the Medical College of Wisconsin. Dr. Hoffmann holds a Ph.D. in Molecular and Cellular Pharmacology from the University of Wisconsin-Madison. He is the recent recipient of the Medical College of Wisconsin ‘Excellence in Science Award’ and has published 7 manuscripts during his graduate and postdoctoral years.